Faculty of Science - Cairo University

Name :   Amal Mohamed Abd El-Megaid Fayed

Date of Birth:       21/1/1966

Nationality:         Egyptian

Previous Degree : M.Sc.

Registration Date :

Awarding Date :            6/1/2008

Supervisors :

Examiners :

Fitle of Thesis :

Prof. Dr. Rasmy Boulos Girgis

Prof. Dr. Helal Saad Helal Abou El-Zahab

Prof. Dr. Hassan Abbas El Mansoury

Prof. Dr. Mohamed Helmy Mohamed Yacout

Prof. Dr. Rasmy Boulos Girgis Prof. Dr. Masanori Yoshioko Prof. Dr. Eberhard Horn

'Studies on detoxification of aflatoxins contaminated rabbits'rations"

Key Words :   Aflatoins - Rabbits - Rations - Contaminated detoxification - ammonia - clay (bentanite) - Poultry litter.

nummary :

The aim of the present study is to investigate the effect of ammonia, clay and poultry itter treatments on detoxification of aflatoxin contaminated rabbits'rations. Five rations control, aflatoxin contaminated ration, contaminated ration treated with ammonia (1%). contaminated ration treated with clay (2%) and contaminated ration treated with poultry itter (1:1) fed to 80 New Zealand male rabbits (16 animals each). The results were ndicated that feeding contaminated ration lead to decrease in CP, OM and NFE contents, increase in ash content and less feeding value (TON) compared to other ations. Rabbits had less feed intake, loss in daily gain, increase in blood AST, ALT, \LP, urea, creatinine and bilirubin. On the other hand, ammoniation and clay bentonite) succeeded in come over the effect of aflatoxins and were comparable with he control group. Internal organs were affected by aflatoxin, where liver, kidneys and leart increased in their weights, while lungs weights were decreased. No detectable Changes were observed in the ammoniated or clay groups. So, ammoniation or clay tddition proved to be recommended as a cheapest way to inhibit the fungus growth and ;an detoxificate its effect in rabbits feeds. While treatment with poultry litter can be :onsidered as the second choice.

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